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The mRNA expression levels of CISD1 in human pan-cancer. (A) CISD1 mRNA expression in various human normal <t>tissues.</t> <t>Genotype</t> Tissue Expression <t>(GTEx)</t> data for CISD1 mRNA in human normal tissues were downloaded from The Human Protein Atlas (THPA) and analyzed using GraphPad Prism. (B) CISD1 mRNA expression in various human cancer tissues. The Cancer Genome Atlas (TCGA) data for CISD1 mRNA expression across different cancer types were retrieved from THPA and analyzed using GraphPad Prism. (C) CISD1 mRNA expression levels in tumor tissues were compared with normal tissues across 33 cancer types. Differential expression analysis was conducted using GEPIA2, with a significance threshold of Q < 0.05 (Benjamini-Hochberg correction for multiple testing). Cancer types with significantly increased CISD1 expression are indicated in brown font, while those with significantly decreased expression are in blue font. N = normal tissue, and T = tumor tissue.
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The mRNA expression levels of CISD1 in human pan-cancer. (A) CISD1 mRNA expression in various human normal tissues. Genotype Tissue Expression (GTEx) data for CISD1 mRNA in human normal tissues were downloaded from The Human Protein Atlas (THPA) and analyzed using GraphPad Prism. (B) CISD1 mRNA expression in various human cancer tissues. The Cancer Genome Atlas (TCGA) data for CISD1 mRNA expression across different cancer types were retrieved from THPA and analyzed using GraphPad Prism. (C) CISD1 mRNA expression levels in tumor tissues were compared with normal tissues across 33 cancer types. Differential expression analysis was conducted using GEPIA2, with a significance threshold of Q < 0.05 (Benjamini-Hochberg correction for multiple testing). Cancer types with significantly increased CISD1 expression are indicated in brown font, while those with significantly decreased expression are in blue font. N = normal tissue, and T = tumor tissue.

Journal: Genes & Diseases

Article Title: Exploring CISD1 as a multifaceted biomarker in cancer: Implications for diagnosis, prognosis, and immunotherapeutic response

doi: 10.1016/j.gendis.2025.101677

Figure Lengend Snippet: The mRNA expression levels of CISD1 in human pan-cancer. (A) CISD1 mRNA expression in various human normal tissues. Genotype Tissue Expression (GTEx) data for CISD1 mRNA in human normal tissues were downloaded from The Human Protein Atlas (THPA) and analyzed using GraphPad Prism. (B) CISD1 mRNA expression in various human cancer tissues. The Cancer Genome Atlas (TCGA) data for CISD1 mRNA expression across different cancer types were retrieved from THPA and analyzed using GraphPad Prism. (C) CISD1 mRNA expression levels in tumor tissues were compared with normal tissues across 33 cancer types. Differential expression analysis was conducted using GEPIA2, with a significance threshold of Q < 0.05 (Benjamini-Hochberg correction for multiple testing). Cancer types with significantly increased CISD1 expression are indicated in brown font, while those with significantly decreased expression are in blue font. N = normal tissue, and T = tumor tissue.

Article Snippet: Genotype Tissue Expression (GTEx) data for CISD1 mRNA in human normal tissues were downloaded from The Human Protein Atlas (THPA) and analyzed using GraphPad Prism. (B) CISD1 mRNA expression in various human cancer tissues.

Techniques: Expressing, Quantitative Proteomics

Quality control of the genotyping dataset. ( a ) Distribution of call rates for the initial 296 samples; ( b ) Distribution of call rates for the final 224 samples; ( c ) Gencall scores at the 10th percentile compared to call rates for the initial 296 samples; ( d ) Gencall scores at the 10th percentile for the remaining 224 samples; ( e ) Gencall scores at the 50th percentile for the initial 296 samples; ( f ) Gencall scores at the 50th percentile for the final 224 samples.

Journal: Scientific Data

Article Title: Genomic landscape of the Great Steppe: Genetic variants in healthy Kazakh individuals

doi: 10.1038/s41597-025-05964-z

Figure Lengend Snippet: Quality control of the genotyping dataset. ( a ) Distribution of call rates for the initial 296 samples; ( b ) Distribution of call rates for the final 224 samples; ( c ) Gencall scores at the 10th percentile compared to call rates for the initial 296 samples; ( d ) Gencall scores at the 10th percentile for the remaining 224 samples; ( e ) Gencall scores at the 50th percentile for the initial 296 samples; ( f ) Gencall scores at the 50th percentile for the final 224 samples.

Article Snippet: Raw genotyping data were downloaded from Macrogen cloud service.

Techniques: Control